microRNA Discovery: A Journey to the 2024 Nobel Prize
May 5, 2025
MicroRNA, a groundbreaking discovery made by Gary Ruvkun and Victor Ambros in the early 1990s, has revolutionized our understanding of gene regulation.Initially overlooked, this tiny RNA molecule is now recognized as a crucial player in the intricate processes that control biological functions across various organisms, including humans.
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Gary Ruvkun: Early Discoveries in Gene Regulation and MicroRNA
April 22, 2025
Nobel Prize winner Gary Ruvkun has significantly transformed our understanding of gene regulation, particularly through his groundbreaking work on microRNA in the model organism Caenorhabditis elegans.In 1992, Ruvkun and his collaborator Victor Ambros uncovered a revolutionary mechanism that governs how genes are expressed, a discovery that would ultimately earn them the 2024 Nobel Prize in physiology or medicine.
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